Detalhe da pesquisa
1.
The Angiotensin AT2 Receptor: From a Binding Site to a Novel Therapeutic Target.
Pharmacol Rev
; 74(4): 1051-1135, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36180112
2.
Assessment of renal fibrosis and anti-fibrotic agents using a novel diagnostic and stain-free second-harmonic generation platform.
FASEB J
; 35(5): e21595, 2021 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33908676
3.
The Novel AT2 Receptor Agonist ß-Pro7-AngIII Exerts Cardiac and Renal Anti-Fibrotic and Anti-Inflammatory Effects in High Salt-Fed Mice.
Int J Mol Sci
; 23(22)2022 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-36430518
4.
The anti-fibrotic actions of relaxin are mediated through AT2 R-associated protein phosphatases via RXFP1-AT2 R functional crosstalk in human cardiac myofibroblasts.
FASEB J
; 34(6): 8217-8233, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297670
5.
Using conformational constraints at position 6 of Angiotensin II to generate compounds with enhanced AT2R selectivity and proteolytic stability.
Bioorg Med Chem Lett
; 43: 128086, 2021 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33965531
6.
N-(Methyloxycarbonyl)thiophene sulfonamides as high affinity AT2 receptor ligands.
Bioorg Med Chem
; 29: 115859, 2021 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33309749
7.
Single Peptide Backbone Surrogate Mutations to Regulate Angiotensin GPCR Subtype Selectivity.
Chemistry
; 26(47): 10690-10694, 2020 Aug 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32691857
8.
Renal functional effects of the highly selective AT2R agonist, ß-Pro7 Ang III, in normotensive rats.
Clin Sci (Lond)
; 134(7): 871-884, 2020 04 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32202299
9.
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a.
Proc Natl Acad Sci U S A
; 114(14): 3750-3755, 2017 04 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28320941
10.
AT1R-AT2R-RXFP1 Functional Crosstalk in Myofibroblasts: Impact on the Therapeutic Targeting of Renal and Cardiac Fibrosis.
J Am Soc Nephrol
; 30(11): 2191-2207, 2019 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-31511361
11.
A Novel Epigenetic Drug-Eluting Balloon Angioplasty Device: Evaluation in a Large Animal Model of Neointimal Hyperplasia.
Cardiovasc Drugs Ther
; 33(6): 687-692, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31885055
12.
ß-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats.
Clin Sci (Lond)
; 129(6): 505-13, 2015 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-26186568
13.
Sex- and age-related differences in the chronic pressure-natriuresis relationship: role of the angiotensin type 2 receptor.
Am J Physiol Renal Physiol
; 307(8): F901-7, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25164079
14.
Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis.
Kidney Int
; 86(1): 75-85, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24429402
15.
The protective arms of the renin-angiontensin system in stroke.
Curr Hypertens Rep
; 16(7): 440, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24816974
16.
The involvement of the Wnt/ß-catenin signaling cascade in fibrosis progression and its therapeutic targeting by relaxin.
Biochem Pharmacol
; 223: 116130, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490518
17.
Hi1a Improves Sensorimotor Deficit following Endothelin-1-Induced Stroke in Rats but Does Not Improve Functional Outcomes following Filament-Induced Stroke in Mice.
ACS Pharmacol Transl Sci
; 7(4): 1043-1054, 2024 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38638162
18.
N-(Heteroaryl)thiophene sulfonamides as angiotensin AT2 receptor ligands.
Eur J Med Chem
; 265: 116122, 2024 Feb 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38199164
19.
Nitroxyl donors retain their depressor effects in hypertension.
Am J Physiol Heart Circ Physiol
; 305(6): H939-45, 2013 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23851276
20.
Update on the angiotensin AT(2) receptor.
Curr Hypertens Rep
; 15(1): 25-30, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23224511